Examples of pharmacokinetic

pharmacokinetic isn’t in the Cambridge Dictionary yet. You can help!
Similar approaches to the minimisation of pharmacokinetic variability are becoming available for other drugs.
Thus, potent, non-peptide inhibitors of metalloproteinases were sought that might have improved pharmacokinetic properties.
As already discussed, the pharmacokinetic characteristics of medication in a 65-year-old may have relatively little relation to patients 80 years of age and beyond.
Second, this is likely more than offset by its pharmacokinetic interactions with protease inhibitors, thus limiting its use in patients on combination antiretroviral therapy (15).
Simultaneously with the testing of pharmacokinetic properties, pharmacodynamic characteristics are also typically investigated in models of the disease the agent is intended to treat.
Pharmacokinetic-pharmacodynamic analysis of antipsychotics-induced extrapyramidal symptoms based on receptor occupancy theory incorporating endogenous dopamine release.
Fluvoxamine shows the least non-linearity of pharmacokinetic parameters, with half-life increasing from about 15 to 23 hours with multiple dosing.
Clinical data are any set of pharmacokinetic and drug response results for single patients or for averages.
Once pharmacokinetic and pharmacodynamic information becomes available, it is possible to use mathematical modelling for testing these protocols and, possibly, for improving them.
Future intra-host models and pharmacokinetic-pharmacodynamic models that include parasite multiplication must therefore incorporate both variation among parasites and individual hosts.
Pharmacokinetic data are collected to determine the half-life, the maximum concentration area under-the-curve, and other parameters.
The pharmacokinetic studies reveal, nonetheless, that supplementation with triiodothyronine results in serum levels which have a nadir at 24 hours.
Pharmacokinetic parameters at baseline and week 12 (month 3) were determined using a noncompartmental analysis.
The pharmacodynamic effects (what the drug does to the body) of aging have been less well evaluated than the pharmacokinetic changes just discussed.
However, no significant influences were conferred by route of administration on any of the pharmacokinetic parameters of albendazole sulphone.
Aging influences all major pharmacokinetic parameters, absorption, distribution, metabolism and excretion.
It could be that the pharmacokinetic features of this compound are not ideal.
Only those agents with pharmacokinetic characteristics suggestive of a compound that can be used successfully in human beings are advanced to the next stage.
Pharmacokinetic data demonstrated that the increase in systemic exposure to tramiprosate was dose related.

随便看

反思网英语在线翻译词典收录了377474条英语词汇在线翻译词条，基本涵盖了全部常用英语词汇的中英文双语翻译及用法，是英语学习的有利工具。