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词汇 oncogenic
释义 BETA

Examples of oncogenic


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This gene was identified by its oncogenic transforming activity.
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Oncogenic fusion genes may lead to a gene product with a new or different function from the two fusion partners.
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Together, their broad inhibitory role may help counter oncogenic signals.
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Generally, oncogenic retroviruses cause transformation of host cells mostly by insertional activation of a host proto oncogene into an oncogene.
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Additionally, adult stem cells derived from bone marrow and cardiac harvest are safe and have never been implicated in immune or oncogenic episodes.
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They were revealed as the transforming principle of oncogenic retroviruses.
Given the long latency, this may be through a promotion effect on randomly occurring oncogenic mutations in the mammary epithelium.
Other molecular relationships between over-expressed 143-3 proteins and different oncogenic molecules have been repeatedly demonstrated.
It is not known whether this represents a fundamental difference in susceptibility for oncogenic transformation of astrocytes compared with cerebellar granule cells.
This indicates a model of tumorigenesis in which granule cells are susceptible to oncogenic transformation during their proliferative phase of development.
There are several compelling arguments against the possibility that the tumour histotype might be defined per se by the specific combination of oncogenic events.
It is possible that these lesions might have acquired additional oncogenic mutations and increased in either size or grade had they been allowed to progress over time.
Forced expression of a single orthotopically expressed wild-type gene is therefore sufficient for oncogenic transformation of the immortalized human mammary epithelial cell.
These contribute to many progresses such as regulation of morphology, gene transcription, proliferation, differentiation, apoptosis and oncogenic transformation.
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After the oncogenic protein is transferred, the recipient cells become transformed and show characteristic changes in the expression levels of target genes.
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