| 词汇 | example_english_telomere-length |
| 释义 | telomere lengthcollocation in Englishmeanings of telomereand lengthThese words are often used together. Click on the links below to explore the meanings. Or, see other collocations with length. telomere noun[C] uk /ˈtiː.lə.mɪər/ us /ˈte.lə.mɪr/ a structure at the end of a chromosome that ... See more at telomere length noun uk /leŋθ/ us /leŋθ/ the measurement of something from end to end or along its ... See more at length Examples of telomere lengthThese examples are from corpora and from sources on the web. Any opinions in the examples do not represent the opinion of the Cambridge Dictionary editors or of Cambridge University Press or its licensors. This view has greater credibility now that biological age can be measured 'scientifically' by, for example, telomerelength. There is also an increasing awareness of the role that telomerelength contributes to human genetic diseases. Additionally, studies have shown that microglia in vivo experience an age-related decrease in telomerelength. Maintenance of telomerelength is essential for chromosome stability, and when telomeres become critically short, with progressive cell division, replicative senescence or apoptosis occurs. Reduction in telomerelength could provide the signal to cause growth arrest. This shortened telomerelength might, however, compromise hepatic regenerative capacity. It has been shown that epigenetic modifications can also regulate telomerelength through the modulation of the chromatin environment of the telomeres themselves. Epithelial stem cells seem also to be regulated by telomerelength and telomerase. Through measurement of telomerelength and telomerase activity in vitro and in vivo we know that microglia are subject to both telomere-dependent and -independent mechanisms of cellular senescence. Both human germ cells and stem cells are considered to be telomerase-positive or competent to express telomerase, and so inhibition of telomerase should affect telomerelength in these cells. Thus, it seems that there is much more variation in the behavior of telomerelength than initially believed. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Population-based studies have also indicated an interaction between anti-oxidant intake and telomerelength. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Telomerelength is associated with the general health of an individual as well as certain diseases, beyond cancer. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Furthermore, the intra-chromosomal distribution of telomerelength in p-arms versus q-arms can be measured. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. This enzyme maintains telomerelength, which results in the telomeres of cancer cells never shortening. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. An additional role in maintaining telomerelength is an active area of investigation. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. These experiments can provide more enlightenment about the role of telomeres and the importance of telomerelength. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. The relation between centromere abnormalities or chromosomal rearrangements and telomerelength may have high clinical impact, since all appear important in pre- or post-natal diagnostics and tumor developments. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Telomerelength varies greatly between species, from approximately 300 base pairs in yeast to many kilobases in humans, and usually is composed of arrays of guanine-rich, six- to eight-base-pair-long repeats. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. These examples are from corpora and from sources on the web. Any opinions in the examples do not represent the opinion of the Cambridge Dictionary editors or of Cambridge University Press or its licensors. Want to learn more? Go to the definition of telomere Go to the definition of length See other collocations with length |
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