词汇 | example_english_surrogate-marker |
释义 | surrogate markercollocation in Englishmeanings of surrogateand markerThese words are often used together. Click on the links below to explore the meanings. Or, see other collocations with marker. surrogate adjective[before noun] uk /ˈsʌr.ə.ɡət/ us /ˈsɝː.ə.ɡət/ replacing someone else or used instead of ... See more at surrogate marker noun[C] uk /ˈmɑː.kər/ us /ˈmɑːr.kɚ/ a sign that shows where ... See more at marker Examples of surrogate markerThese examples are from corpora and from sources on the web. Any opinions in the examples do not represent the opinion of the Cambridge Dictionary editors or of Cambridge University Press or its licensors. The availability of such a surrogatemarker would considerably enhance our abilities to rationally design new therapies directed towards minimal residual disease. This procedure meant that we had to rely on surrogatemarker changes for some patient group guideline combinations and on clinical events for others. In future clinical trials, evaluation of remyelination will require a reliable and quantifiable myelin marker to be used as a surrogatemarker. Race may be a surrogatemarker for other, unmeasured, factors such as access to health care. A major impediment to successful islet transplantation in humans is the lack of a suitable surrogatemarker to detect a rejection response as soon as it occurs. Delivery prior to 37 weeks gestation was felt to be a surrogatemarker for the severity of the pre-eclampsia. However, high-dose diuretic use is likely to be a surrogatemarker of more advanced cardiac failure and hence explain, at least in part, this poorer outcome. As prenatal nutrition is difficult to measure, birth weight has been used as a surrogatemarker of nutrition in many studies. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Death from heart disease is the endpoint of interest, but cholesterol is the surrogatemarker. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. The downstaging is then a surrogatemarker of efficacy on undetected dissemination, resulting in improved longtime survival compared to the surgery-alone strategy. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Deficiencies in medical supervision are suggested by several surrogate markers of which the poorly controlled use of neuroleptic medication11,12 is a good example. In addition, the third element, outcome, may mislead when surrogate markers are used in place of clinically meaningful outcomes (16). For example, surrogate markers of socio-economic status, such as benefit claims, are often used. To date, many studies have investigated the role of infection in the development of cerebral palsy by using surrogate markers of infection, such as chorioamnionitis and maternal pyrexia. Involvement of health outcomes specialists early in product development allows modeling to identify key endpoints and surrogate markers that most closely predict final outcomes of treatment. These examples are from corpora and from sources on the web. Any opinions in the examples do not represent the opinion of the Cambridge Dictionary editors or of Cambridge University Press or its licensors. Want to learn more? Go to the definition of surrogate Go to the definition of marker See other collocations with marker |
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