| 词汇 | example_english_downstream-target |
| 释义 | downstream targetcollocation in Englishmeanings of downstreamand targetThese words are often used together. Click on the links below to explore the meanings. Or, see other collocations with target. downstream adjective adverb uk /ˌdaʊnˈstriːm/ us /ˌdaʊnˈstriːm/ in the direction a river or stream ... See more at downstream target noun uk /ˈtɑː.ɡɪt/ us /ˈtɑːr.ɡɪt/ an object shot at during shooting practice, often a circle with a pattern of rings, or any object or place at which bullets, bombs, etc. ... See more at target Examples of downstream targetThese examples are from corpora and from sources on the web. Any opinions in the examples do not represent the opinion of the Cambridge Dictionary editors or of Cambridge University Press or its licensors. We used multiple regressions where the downstreamtarget is a predicted value and upstream splicing factors are predictor variables. The downstreamtarget delivers the snapshot to the next target, as in the push model. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. It influences cellular physiologic processes by regulating the expression of downstreamtarget genes, which are related to growth, survival, and other cellular activities. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. In three-kinase signaling cascades, scaffolds bind all three kinases, enhancing kinase specificity and restricting signal amplification by limiting kinase phosphorylation to only one downstreamtarget. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Brn3a is a transcription factor which acts in development by regulating downstreamtarget genes. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. This observation could suggest that these genes are downstream targets of the genetic changes that cause hybrid male sterility in these species. However, the phosphorylation o f some downstream targets occurs in a phosphoinositide-dependent manner through modificati on of its substrates. The mechanism for this failure is not clear but is likely to involve dysregulation of downstream targets. However, it is unknown whether a 2-fold or 10-fold reduction in its expression would necessarily cause underexpression of its downstream targets or sterility. Nutrition-sensitive hypothalamic neuropeptides are the most prominent downstream targets of leptin. It is clear that matrix-degrading proteases are essential for tumour progression, but it is not known whether they all act in independent pathways or have some common downstream targets. Downstream targets of this pathway are upregulated and these ensure the transition to the second phase. Its activation mechanism and downstream targets are still not well characterized. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. They help stabilize catenin, which activates downstream targets. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Once they occur as duplicates, accumulated mutations encoding for one copy can take place without negatively affecting the regulation of downstream targets. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. These kinases phosphorylate downstream targets in a signal transduction cascade, eventually leading to cell cycle arrest. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. These examples are from corpora and from sources on the web. Any opinions in the examples do not represent the opinion of the Cambridge Dictionary editors or of Cambridge University Press or its licensors. Want to learn more? Go to the definition of downstream Go to the definition of target See other collocations with target |
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