词汇 | antigenic |
释义 | antigenic adjective medical specializeduk /ˌæn.tɪˈdʒen.ɪk/ us /ˌæn.t̬ɪˈdʒen.ɪk/ relating to or consisting of antigens(= substances that cause the body's immune system to react, especially causing it to produce antibodies): 抗原的 The flu vaccine's antigenic configuration changes yearly and is based on prevalent strains of the preceding year. 流感疫苗的抗原结构每年都会发生变化,并以上一年流行的菌株为基础。 Vaccination is not always effective, because a virus develops different strains with varying antigenic properties. Related word antigen The virus in an inactivated vaccine has lost the capacity to replicate but can stimulate antibodies, because of its antigenic nature. A specific test for diagnosing the antigenic sensitivity responsible for the allergic symptoms is described. Researchers carried out phylogenetic and antigenic analysis of influenza viruses. Immunology & vaccination active immunity ANA anti-vax antibody antigen antinuclear antibody antiserum herd immunity immune response immunity immunization immunocompromised immunosuppressed inoculation lymph unimmunized uninoculated unvaccinated vaccinated vaccination Examples of antigenicantigenic Differences in the level of surface exposed molecules may also contribute to phenotypic and antigenic variation of the pathogen. The second strategy (antigenic variation) is defined as periodic modification of surface antigens within a single developmental phase. Rapid switching to multiple antigenic and adhesive phenotypes in malaria. The monoclonal antibody reaction pattern for antigenic variants 1 and 4 and the number of isolates for each vertebrate host are shown. Whether the antigenic variants arise in an ordered sequence or randomly has been in dispute but has not been statistically tested. Vaccination must be updated yearly, in order to take into account the genetic/antigenic evolution of wildtype influenza viruses. Three different var gene switching mechanisms are investigated and are based on experimental observations of clonal antigenic variation in malaria parasites. Clinical vaccine trials will have to be undertaken with caution since questions about the offending responsible antigenic moiety of the organism also remain unanswered. These differences include their infectivity in host cells, virulence and pathogenesis in animal models, drug sensitivity, tissue tropism, morphology, and antigenic composition. This might be relevant for significance of results where animals are immunized with complex antigenic mixtures. It is helpful at the outset to make a clear distinction between two senses of the term ' antigenic variation ' when applied to pathogens. Even the proteinases released by various gastrointestinal nematodes have previously been shown to be highly antigenic and targets of protective immunity. In other words, practically all individuals would receive an antigenic stimulus and therefore mount a new response before the antibody concentration decreased below this level. This has important structure-function implications for the protein, as well as for defining antigenic fragments best suited for vaccine design and development. This chronic antigenic stress and the subsequent inflammatory burden have a major impact on survival and frailty. These examples are from corpora and from sources on the web. Any opinions in the examples do not represent the opinion of the Cambridge Dictionary editors or of Cambridge University Press or its licensors. |
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