词汇 | electroporation |
释义 | electroporation noun[ U ] biology, medical specializeduk /iˌlek.trəʊ.pəˈreɪ.ʃən/ us /iˌlek.trə.pɚˈreɪ.ʃən/ the act or process of using a short current of electricity to open the pores(= small holes in the surface) of a cell or other living surface in order to allow something such as DNA or a drug to pass into the cell: (在细胞或其他活组织表面)电穿孔 With current methods of electroporation, the procedure is not commercially viable on a large scale.以目前的电穿孔方法,该方法在大规模商业上是不可行的。 The company is developing the use of electroporation as a delivery tool for certain vaccines. Electroporation is being developed by the pharmaceutical industry as a better way to drive drugs into the cells. Electroporation and other technologies are able to get more of the drugs into cells. The mice received a single dose of the DNA vaccine delivered by electroporation. Immunology & vaccination active immunity ANA anti-vax antibody antigen antigenic antinuclear antibody herd immunity immune response immunity immunization immunocompromised immunosuppressed inoculation lymph unimmunized uninoculated unvaccinated vaccinated vaccination Examples of electroporationelectroporation The nuclear genome has been transformed with both glass bead agitation and electroporation. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. When used for the delivery of transcription factors, the microfluidic devices produced a 10-fold improvement in colony formation relative to electroporation and cell-penetrating peptides. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Using electroporation or centrifugation to insert drugs into microvesicles targeting specific cells, it is possible to target the drug very efficiently. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. The oocytes were removed from the electroporation medium 2 min after electrical pulse. Expressing the gene in neural crest cells by electroporation, inhibits migration of neural crest cells into the trigeminal ganglia, and prevents differentiation into neurons or other differentiated cells. After over-expression by electroporation into the cranial neural tube and neural crest, we observed a marked redistribution of electroporated neural crest cells in the vicinity of the trigeminal ganglion. It should be noted that both the retroviral system and electroporation system allow for the efficient genetic alteration of retinal progenitor cells in vivo at different developmental stages. He has also developed electroporation techniques, a method for pulsed-field electrophoresis, and methods for analyzing microarray data. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Although electroporation and dielectric breakdown both result from application of an electric field, the mechanisms involved are fundamentally different. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Another transformation method for plant and animal cells is electroporation. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Fusion can also be artificially induced through electroporation in a process known as electrofusion. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. It has even been proposed that electroporation resulting from lightning strikes could be a mechanism of natural horizontal gene transfer. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Transformation using electroporation was developed in the late 1980s, increasing the efficiency and bacterial range. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Contrastingly, reversible electroporation occurs when the electricity applied with the electrodes is below the electric field threshold of the target tissue. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. With optimized protocols, over 50% of the cells that survive electroporation contain the desired change. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. These examples are from corpora and from sources on the web. Any opinions in the examples do not represent the opinion of the Cambridge Dictionary editors or of Cambridge University Press or its licensors. |
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