Examples of docetaxel

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To assess the rates of axillary lymph node metastases and breastconserving procedures following 3 versus 6 cycles of epidoxorubicin (short infusion)/docetaxel (1-hour infusion).
To define gene expression profiles that can predict a recurrence-free survival advantage for either dose dense therapy, or docetaxel - containing chemotherapy.
Given the uncertain long-term outcomes of this population, and the high rates of cardiotoxicity, this regimen of docetaxel cisplatin trastuzumab followed by doxorubicin with cyclophosphamide cannot be recommended.
Comparison of vinorelbine versus docetaxel, and trastuzumab versus no trastuzumab as adjuvant treatments of early breast cancer.
To assess tolerability, safety and efficacy of trastuzumab given concomitantly with vinorelbine or docetaxel as adjuvant treatment of early breast cancer with moderate to high risk for cancer recurrence.
To compare the hematological toxicity and efficacy of sequential versus concomitant administration of doxorubicin and docetaxel as metastatic breast cancer first-line treatment.
To assess the toxicity and efficacy of the combination of docetaxel and gemcitabine every 2 weeks as first-line therapy in metastatic breast cancer.
A docetaxel cycle is defined as 6-weekly docetaxel infusions followed by 2 weeks without treatment (8 weeks).
To assess the adverse event profile of the weekly dose dense combination of docetaxel and irinotecan.
To evaluate the efficacy and the toxicity profile of the sequential administration of doxorubicin and docetaxel as first-line chemotherapy in metastatic breast cancer.
Quality of life in patients with metastatic breast cancer receiving either docetaxel or sequential methotrexate and 5-f luorouracil.
It is planned to administer 2 docetaxel cycles prior to primary breast surgery.
To assess the anti-tumor activity of a dose dense regimen of docetaxel and irinotecan for patients with refractory breast cancer.
A monoclonal antibody that binds anionic phospholipids on tumor blood vessels enhances the antitumor effect of docetaxel on human breast tumors in mice.

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