词汇 | codon |
释义 | codon noun[ C ] biology specializeduk /ˈkəʊ.dɒn/ us /ˈkoʊ.dɑːn/ a set of three nucleotides that together form a unit of genetic code in a DNA or RNA molecule(基因的)密码子 Genetics accession number adenine anaphase autosomal autosomally genetic fingerprinting genetically engineered geneticist genic genomic genomics genotypic monozygotic mutate non-familial non-genetic non-mutant nondominant nonhomologous sex-linked You can also find related words, phrases, and synonyms in the topics: Biochemistry codon | American Dictionarycodon noun[ C ] us/ˈkoʊ·dɑn/ biology a group of three chemical substances in DNA that contains the information for one of the amino acids, which are necessary for making protein (= substance necessary for the body to grow) Examples of codoncodon This analysis helped to locate the position of the translation start codon more precisely. Finally, all 38 isolates encoded isoleucine at codon 356. Thus, the third codon position was excluded from further analysis. Conversely, according to the selective model, recombination should improve the efficacy of selection against all non-optimal codons. Hence, there is no evidence that recombination increases the efficacy of selection against non-optimal codons. For these comparisons, analyses were effected on the alignment including all codon positions. Finally, the fragment including the putative initiation codon was obtained and sequenced. The second difficulty is the way to define the contribution of each codon to the fitness of a genome. The initial codon is indicated in bold capital letters and stop codons in bold lower-case letters. The remaining 25% are mainly third base substitutions in codons which are silent (synonymous nucleotide substitutions). Nucleotide substitutions were mainly transitions and most of them occurred at the third codon. Although the number of clones was limited caused by specimen availability, the analysed codon utilization did not have a strong bias. Therefore, major codons should be more beneficial (and therefore, fixed in the population) in highly expressed genes. In addition, the antigen of interest is often 'codon optimised' to improve expression levels. For a number of organisms, evidence suggests that biased codon usage reflects the action of selection to maximize translational efficiency and accuracy. These examples are from corpora and from sources on the web. Any opinions in the examples do not represent the opinion of the Cambridge Dictionary editors or of Cambridge University Press or its licensors. |
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