| 词汇 | cisplatin |
| 释义 | cisplatin noun[ U ] medical specializeduk /sɪsˈplæt.ɪn/ us /sɪsˈplæt̬.ən/ a drug injected into the veins in the treatment of certain types of cancer（注射入静脉用于治疗某些癌症的）顺铂 Specific types of drug acaricide alprazolam amnesiac anaphrodisiac anti-AIDS designer drug digoxin dissociative E, e ecstasy gas and air GHB heroin LSD pep pill popper roach smack truth serum Xanax Examples of cisplatincisplatin Delayed emesis can persist up to five days after cisplatin administration, peaking in intensity at 48 to 72 hours. This balanced perspective on the impact of this novel could increase capacity in a service stretched to provide adequate cisplatin provision. The first cisplatin analog to be developed was carboplatin. The toxicity profile mirrored that of cisplatin alone with the most common toxicities being cytopenias (n 10), nausea/vomiting (n 9), and asthenia (n 5). Clinical trials have since established cisplatin in lung, ovarian, esophageal, cervical, head and neck and germ cell cancers. For this reason, cisplatin-induced emesis has become the human model by which antiemetic regimens are evaluated (7). Like other traditional chemotherapeutic agents, cisplatin has untoward side-effects (nephrotoxicity, ototoxicity, and neuropathy) and clinical drug resistance does occur. Acute emesis usually begins 2 to 4 hours after cisplatin administration and peaks at 6 hours (23;26). Unfortunately, carboplatin shows a marked degree of cross-resistance when compared to cisplatin. Epidermal growth factor receptor pathway analysis identifies amphiregulin as a key factor for cisplatin resistance of human breast cancer cells. The results of our study show that cisplatin has no effect on either minisatellite mutations or crossover frequencies during the most important stages of mouse spermatogenesis. In the case of antineoplastic agents such as paclitaxel, cisplatin and thalidomide, the neuropathy is dose-dependent and doselimiting; patients often cannot tolerate the doses necessary to treat the underlying cancer. Carboplatin costs £205.71 against £17.90 for cisplatin, but the total treatment costs are reduced from £347.90 to £228.77. From the Hansard archive Example from the Hansard archive. Contains Parliamentary information licensed under the Open Parliament Licence v3.0 This research is especially useful for cancer patients because chemotherapy drugs, such as cisplatin, cause nausea and vomiting. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Drugs with medium risk include doxorubicin and platinum analogs such as cisplatin and carboplatin. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. These examples are from corpora and from sources on the web. Any opinions in the examples do not represent the opinion of the Cambridge Dictionary editors or of Cambridge University Press or its licensors. |
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