| 词汇 | chloroquine |
| 释义 | BETA Examples of chloroquinechloroquine isn’t in the Cambridge Dictionary yet. You can help! Similar hitch-hiking events could thus be expected to apply in view of the involvement of pfmdr-1 in high level chloroquine-resistance. This may reflect a genetically diverse origin of chloroquine resistance. This suggests involvement of additional genetic loci in modulating chloroquine resistance. They were considered to have chloroquine-resistant parasites and were treated with a course of sulphadoxine\\pyrimethamine. To calculate the life-span of gametocytes we considered the gametocyte density data from the chloroquine group only. In the chloroquine group asexuals were not observed post-treatment. This compound and other macrolides merit future investigation of their possible use in combination with chloroquine in areas of chloroquine-resistant malaria. Identifying reliable markers of chloroquine resistance is important to inform both individual malaria treatment and local drug policy. This prompted intervention by the health authorities (mass drug administration using chloroquine and primaquine and spraying of residual insecticides in homes). Most clinical cases (14\\22) cleared their parasites 3 days after starting treatment with chloroquine. Chloroquine could only affect female gametocytes more than males if they metabolise haematin for a longer period. We stopped gametocyte production with chloroquine in order to study a cohort of gametocytes in vitro. The differing impact of chloroquine and pyrimethamine/ sulfadoxine upon the infectivity of malaria species to the mosquito vector. An alternative explanation for our results is that chloroquine could exert different effects on male and female gametocytes. The density in the chloroquine group decreased at a significantly faster rate than the control group. |
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