| 词汇 | scrapie |
| 释义 | scrapie noun[ U ] uk /ˈskreɪ.pi/ us /ˈskreɪ.pi/ a serious brain disease of sheep and goats that usually results in death痒病（绵羊和山羊的一种严重脑病，通常可致死） Zoology: veterinary medicine acaricide altered animal doctor anti-rabies bovine spongiform encephalopathy BSE castrate cowpox emasculate lame mange mangy monkeypox mpox myxomatosis neutered nosema put something/someone down veterinarian worm Examples of scrapiescrapie Previous, often intensive control programmes have foundered, and we cannot point to a clear-cut example of successful large-scale scrapie control. In this paper we develop a method to fit stochastic transmission models to outbreak data and explore its use by analysing a high-incidence scrapie epidemic. At the within-flock level, we describe scrapie transmission using a stochastic model incorporating the available data on pathogenesis, sheep demography, genetic susceptibility and incubation times. Data are either right-censored for scrapie deaths, representing non-scrapie morality only (solid lines), or include scrapie mortality (broken lines). However, we note that the dynamics of the disease in goats is likely to be highly dependent on sheep scrapie. Immunological comparison of scrapie-associated fibrils isolated from animals infected with four different scrapie strains. In future research, similar model analyses of data on less severe scrapie epidemics should provide more detailed information. Replication of distinct scrapie prion isolates is region specific in brains of transgenic mice and hamsters. This will serve as a starting point for the future study of scrapie persistence in a population consisting of a large number of interacting flocks. These data are simultaneously analysed using mathematical models describing scrapie transmission between sheep and between flocks. At present, given the uncertainities surrounding the transmission characteristics of scrapie, it is important to consider a broad variety of different transmission scenarios. During this period a total of 304 scrapie cases occurred. Below we will also compare the population-level prevalence of scrapie infection between various within-flock transmission scenarios. Structural studies of the scrapie prion protein using mass spectrometry and amino acid sequencing. Of more interest is the prediction of the number of non-case farms that currently harbour undetected scrapie. These examples are from corpora and from sources on the web. Any opinions in the examples do not represent the opinion of the Cambridge Dictionary editors or of Cambridge University Press or its licensors. |
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