Examples of retinoblastoma

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Studies of mixed diagnoses were included if outcomes were reported separately for children with retinoblastoma.
However, there was only one observed case of trilateral retinoblastoma in the study.
These mice have since been used to test new chemotherapeutic drug combinations for the treatment of retinoblastoma.
This is the first time that new drugs have been incorporated into a clinical trial for retinoblastoma accompanied by a complete preclinical laboratory analysis.
The retinoblastoma tumor suppressor modifies the therapeutic response of breast cancer.
The most common presenting sign of retinoblastoma is leukocoria (a lack of normal red reflex of the eye).
The aim of this systematic review was to establish the evidence base for treatments for retinoblastoma in children.
Both children had undergone monocular enucleation during infancy for retinoblastoma.
Intraretinal xenografts of differentiated human retinoblastoma cells integrate with the host retina.
Genetic screening was considered cost-saving for familial adenomatous polyposis with high health economic evidence and for retinoblastoma and insulin-dependent diabetes mellitus with limited evidence.
Historically, enucleation was the standard treatment used for cases of unilateral retinoblastoma.
The mechanism by which an imprinting defect might be linked to retinoblastoma is still unclear.
Aberrant nucleocytoplasmic localization of the retinoblastoma tumor suppressor protein in human cancer correlates with moderate/poor tumor differentiation.
Few data on adverse effects of treatment interventions for childhood retinoblastoma were available from the included studies.
One retrospective study compared two different chemotherapy regimens for the treatment of extraocular retinoblastoma (6).
Two prospective studies compared two different chemotherapy regimens in patients with intraocular retinoblastoma (2;18).
Tumor formation in mice with somatic inactivation of the retinoblastoma gene in interphotoreceptor retinol binding protein-expressing cells.

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