| 词汇 | adenovirus |
| 释义 | adenovirus noun[ C or U ] medical specializeduk /ˈæd.ɪ.nəʊˌvaɪə.rəs/ us /ˌæd.ɪ.noʊˈvaɪ.rəs/ one of a group of viruses that cause many different illnesses, especially respiratory(= breathing) diseases呼吸系统病毒 Bacteria, moulds, germs & viruses abacterial acquired immune deficiency syndrome acquired immunodeficiency syndrome aerobe AIDS virus amoeba bacteriology fly agaric germicidal germophobe gnotobiotic Gram-negative listeria microbe probiotic reindeer moss respiratory syncytial virus retroviral root rot rotavirus Examples of adenovirusadenovirus Transcriptional targeting modalities in breast cancer gene therapy using adenovirus vectors controlled by alpha-lactalbumin promoter. Although animals were injected with the same amount of recombinant adenovirus, the level of expression detected depended on the individual promoter activity. Because adenovirus is a commonly occurring virus, most humans are pre-primed to at least one specific serotype. Repeated administration of a therapeutic adenovirus must be performed, which could result in an inflammatory response in the patient. Separating fact from fiction: assessing the potential of modified adenovirus vectors for use in human gene therapy. The other viral outbreaks (rotavirus and adenovirus) were all transmitted by person-toperson contact. Image reconstruction reveals the complex molecular organisation of adenovirus. Adenovirus-mediated gene delivery and in vitro microinsemination produce offspring from infertile male mice. The ferritin transgenes were delivered using a replicative-deficient adenovirus. Adenovirus-mediated gene transfer transiently corrects the chloride transport defect in nasal epithelia of patients with cystic fibrosis. An optimal animal model of the immunological challenges associated with human clinical trials for gene therapy would involve immunization with a wild-type, replicating, human adenovirus. Replication-defective recombinant adenoviruses are the second most commonly used viral vectors in clinical trials today. First-generation adenovirus can be engineered with powerful promoters to drive expression of therapeutic transgenes. Nonintegrating viruses, like adenoviruses, have the disadvantage that they remain episomal and can be lost during cell division. For the systemic immunization to eliminate transgene expression from the brain, >16107 infectious units (iu) of adenovirus need to be used as immunogen. See all examples of adenovirus These examples are from corpora and from sources on the web. Any opinions in the examples do not represent the opinion of the Cambridge Dictionary editors or of Cambridge University Press or its licensors. |
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