| 词汇 | plasminogen |
| 释义 | plasminogen noun[ U ] anatomy specializeduk /plæzˈmɪn.ə.dʒən/ us /plæzˈmɪn.ə.dʒən/ a chemical found in blood that can be changed into plasmin(= a chemical that dissolves blood clots) by a chemical reaction when needed : plasminogen activatorPlasminogen activators are involved in many protein degrading processes by converting plasminogen into the active enzyme plasmin. The clot-busting plasminogen activator is only approved for use within three hours of onset of the symptoms of a stroke. Plasmin is produced by the cleavage of a single peptide bond of the inactive precursor, plasminogen. Fibrinolytic drugs work by activating plasminogen to form plasmin, which degrades fibrin and so breaks up the clots. Treatment with intravenous plasminogen has been shown to be beneficial in case studies. The circulatory system & blood ABO accessory pathway adventitia adventitial ANA auricle bicuspid valve femoral artery gamma globulin glomus granulocyte haematogenous haemic phagocyte precava pulmonary artery pulmonary vein pulmonic Purkinje fibre tricuspid valve Examples of plasminogenplasminogen So we added the intracoronary thrombolytic therapy using tissue-type plasminogen activator. In contrast to others, we chose to use tissue plasminogen activator instead of steptokinase. Plasminogen-deficiency states associated with the complete absence of plasminogen, as well as dysplasminogenaemias associated with reduced plasmin activity, have been described in humans. Our report discusses policies for postoperative prophylaxis as well as treatment of the acute thrombosis, including thrombolytic therapy with tissue plasminogen activator. The proteolytic plasminogen/plasmin system has now begun to be taken into account in the fertilization process. The inhibition of plasminogen activation by apo(a) might contribute to the development of atherosclerosis by inhibiting fibrinolysis or some other activity of plasmin. First we used intravenous administration of tissue-type plasminogen activator. Immunological relationship between the fastacting plasminogen activator inhibitors from plasma, blood platelets and endothelial cells demonstrated with a monoclonal antibody against an inhibitor from placenta. Involvement of the plasminogen activator/plasmin proteolytic cascade in fertilization. During bypass endothelial cells produce tissue plasminogen activator,21 probably in response to small quantities of circulating thrombin (not proven). Echocardiographic diagnosis was followed by infusion of tissue plasminogen activator (dosage as above). The insulin-like growth factor-1 elevates urokinase-type plasminogen activator-1 in human breast cancer cells: a new avenue for breast cancer therapy. The activator cleaves plasminogen to produce plasmin, the primary plasma fibrinolytic enzyme. The dose of tissue plasminogen activator administrated was 0.4-1.0 mg/kg. Thrombolytic therapy with streptokinase (or, if contraindicated, tissue plasminogen activator) was used in eight patients, with success being achieved in four. These examples are from corpora and from sources on the web. Any opinions in the examples do not represent the opinion of the Cambridge Dictionary editors or of Cambridge University Press or its licensors. |
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