Examples of pharmacokinetics

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It is evident that children have a higher metabolic rate than adults and, therefore, will have differences in their pharmacokinetics.
However, modified drug pharmacokinetics occurring with age may influence drug tolerance at standard doses.
In addition, the pharmacokinetics of the antibiotics change, which might lead to sub-therapeutic levels for the antimicrobials for which serum levels are not monitored.
The pharmacokinetics of drugs is modified in elderly patients at different levels: absorption of drug, distribution, metabolism and excretion.
Section one gives a nice introduction to brain development and pharmacokinetics for clinicians looking to update their knowledge.
Metabolites, pharmacodynamics and pharmacokinetics of tamoxifen in rats and mice compared to the breast cancer patient.
In addition, appropriate pharmacokinetics and safety margins of the drugs should be considered when treating patients with liver disease.
A typical chapter is structured into history, botany, constituents, pharmacokinetics, mechanisms of action, physiological effects, toxicity and conclusions.
Finally, a table is provided for guiding the optimal choice of dosing intervals under different values of population pharmacokinetics, drug resistance and individual immunity parameters.
The dynamics of drug action on the within-host population growth of infectious agents : melding pharmacokinetics with pathogen population dynamics.
An overview of the pharmacology and pharmacokinetics of the newer generation aromatase inhibitors anastrozole, letrozole and exemestane.
These agents might have a significant advantage with respect to pharmacokinetics and minimisation of side effects.
The effect of ageing on the pharmacokinetics and pharmacodynamics of prazocin.
Pharmacokinetics of mefloquine combined with artesunate in children with acute falciparum malaria.
First, the pharmacokinetics of sertraline is the same in both elderly and younger patients.

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