| 词汇 | binding-site |
| 释义 | binding site noun[ C ] biology specializeduk /ˈbaɪn.dɪŋ ˌsaɪt/ us /ˈbaɪn.dɪŋ ˌsaɪt/ an area on an enzyme, DNA or RNA to which particular molecules or ions attach结合位点 Examples of binding sitebinding site The findings are more consistent with a pathway than with a fixed bindingsite. The activity of cyclic nucleotide analogs is informative regarding the nature of the bindingsite and the structural requirements for ligand activity. We discussed both the classical approach, assuming distributed binding sites in a smeared layer and a one-binding-site model. Most lipocalins are beta-barrel structures with only one bindingsite for hydrophobic molecules. Once assembled, the terminal regions are folded to become the bindingsite for the next subunits. The nucleotide bindingsite is located in a pocket between the two domains. This analysis should quantitatively reflect the free energy surface sampled by the ligand as it is pulled through the bindingsite. More experiments investigating the nucleoside specificity of this bindingsite is under progression in our laboratory. Favorable positions of functional groups in a bindingsite can be found and even novel minima, which are not present in the fixed structure. These regions have been classified by the strength with which water is bound and the nature of the bindingsite. As documented above, one is where the short motifs overlap and combine to perform a single bindingsite. This is a strong argument for a bindingsite outside the pore. The charges are shown arranged nonspecifically to emphasize that such a mechanism is not dependent upon the existence of a specific bindingsite or pocket. Residues outside the bindingsite are represented by surface plot. A bindingsite identified by these assays, however, does not necessarily represent a functional target in vivo. See all examples of binding site These examples are from corpora and from sources on the web. Any opinions in the examples do not represent the opinion of the Cambridge Dictionary editors or of Cambridge University Press or its licensors. |
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