词汇 | neurodegenerative |
释义 | neurodegenerative adjective medical specializeduk /ˌnjʊə.rəʊ.dɪˈdʒen.ə.rə.tɪv/ us /ˌnʊr.oʊ.dɪˈdʒen.ə.rə.t̬ɪv/ involving the nerves gradually stopping working: 神经组织退化的 neurodegenerative disease神经退行性疾病 Disorders of muscles & the nervous system acoustic neuroma ageusia agraphia akinetic-rigid HD alexia CJD comatose dysgraphia dysphasia dysphasic dysphonia dyspraxia leprosy neuralgia NMO palsy Parkinson's parosmia peripheral nerve injury shin splints Examples of neurodegenerativeneurodegenerative This study demonstrates several aspects of the evolution of clinical trial methodologies to assess potentially disease-modifying agents in patients with neurodegenerative disorders. These observations suggest that the expression of astrocyte connexins varies during the progression of this neurodegenerative disease. Recent years have seen the identification of many genetic defects that underlie hereditary neurodegenerative disorders in humans. Microglia have been implicated in aging-related neurodegenerative disease, yet relatively little is known about how normal aging and chronic pathological states may affect microglial function. Consequently, insulin abnormalities may disrupt normal memory functioning and promote pathophysiological processes observed in patients with neurodegenerative disorders. Potentially reversible impairments are likely to precede the neurodegenerative changes that characterize dementia. Excitotoxicity appears to play a role in both neurodegenerative and cerebrovascular diseases. There is substantial evidence that such reactive and inflammatory responses make significant contributions to neuronal damage in neurodegenerative diseases. This may reflect an independent relationship or the interaction of neurodegenerative pathology with vascular changes. Other neurodegenerative diseases fail to support the proposal that amyloid fibrils are pathogenic. It is a neurodegenerative syndrome that involves a slow decline in various aspects of the nervous system and memory function. Underlying neurodegenerative processes, which may be pathological or age-related, are thought to be the most likely explanation. A distinction between healthy, activated microglia and dysfunctional, senescent cells is crucial when considering future approaches to maintain brain health and treat neurodegenerative disease. Information about how best to intervene in protein-misfolding disorders may result in principles applicable across many neurodegenerative disorders. These phenomena may correlate with overloading of memory capacity due to neurodegenerative changes. See all examples of neurodegenerative These examples are from corpora and from sources on the web. Any opinions in the examples do not represent the opinion of the Cambridge Dictionary editors or of Cambridge University Press or its licensors. |
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