词汇 | mutagenesis |
释义 | BETA Examples of mutagenesismutagenesis isn’t in the Cambridge Dictionary yet. You can help! However, principles of evolutionary biology suggest a far more powerful approach, based on a combination of mutagenesis and recombination. Modification of the reactivity of spinach chloroplast thioredoxin f by site-directed mutagenesis. Mutagenesis, screening and genetic analysis of the mutants. Second the sampling error in free-energy difference calculations of mutagenesis in the free state and in complex was checked. The book is divided into three main sections, somaclonal variation, mutagenesis and molecular analysis techniques. We have embarked upon a major mouse mutagenesis programme to recover a large number of novel mutant phenotypes, including new mouse deaf mutants. In summary, we used random chemical mutagenesis and screening to find a mouse model for autosomal dominant retinitis pigmentosa. Large numbers of mice established by in vitro fertilization with cryopreserved spermatozoa: implications and applications for genetic resource banks, mutagenesis screens and mouse backcrosses. His mutagenesis work once again proved valuable in unravelling a biological phenomenon. In this experimental system, mutagenesis was followed by eight generations of growth in a mass culture when mutations with large heterozygous effects would be out-competed. Large-scale mutagenesis of the mouse to understand the genetic bases of nervous system structure and function. These ideas now need to be tested using site-directed mutagenesis. Conformational heterogeneity of an equilibrium folding intermediate quantified and mapped by scanning mutagenesis. The label site can be selected and varied by site-directed mutagenesis, provided the structure and function of the protein are not disturbed. This measure may be augmented by site directed mutagenesis, altering the helix content by changes in capping interactions or in propensities for helix formation. Finally, conclusions concerning the likely governing chemistry can be directly tested with site-directed mutagenesis. Targeted mutagenesis in mammalian cells mediated by intracellular triple helix formation. |
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