英语词汇“misfolded”的音标、意思、用法及中文翻译-反思网

Examples of misfolded

Misfolded

misfolded

This example is from Wikipedia and may be reused under a CC BY-SA license.
The affected protein may be misfolded or truncated, or it may contain an expanded repeat or amino acid substitution.
The multivalent nature of this binding could potentially contribute to reversing misfolded states.
Exactly how the misfolded proteins trigger oligodendrocyte apoptosis and why they are harmful to the cell is currently uncertain.
The other path involves a species that is misfolded and has to rearrange in an even slower step before the properly folded structure is reached.
Interactions involving the exposed hydrophobic surfaces of misfolded protein conformers lead to the formation of toxic aggregates, including oligomers, protofibrils and amyloid fibrils.
The red asterisk represents a site of modification on the misfolded protein as a result of one of these stresses.
In some cases, chaperones promote the correct folding of their misfolded protein substrates.
Complex formation with the chaperone thus allows the correction of misfolded conformations in an isolated environment without the danger of intermolecular aggregation reactions.
Strikingly, the transgenic rats showed that misfolded protein tau triggered massive inflammatory response characterized by activation of microglia and macrophages.
Moreover, paths that lead to misfolded, kinetically trapped species can also be seen.

词汇	misfolded
释义	BETA Examples of misfolded misfolded isn’t in the Cambridge Dictionary yet. You can help! Misfolded structures can be stable, and kinetically trapped species often transiently accumulate in refolding experiments. Is there 'plasticity' in the folding process upon interaction of the misfolded protein with a pharmacological chaperone? It is likely that neurotoxicity is caused by the misfolded protein in its soluble form, and/or in aggregates, and/or in the process of aggregation. Protein misfolding: optional barriers, misfolded intermediates, and pathway heterogeneity. The formation of illegitimate sulfide bonds creates a misfolded protein, resulting in loss of function. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. The affected protein may be misfolded or truncated, or it may contain an expanded repeat or amino acid substitution. The multivalent nature of this binding could potentially contribute to reversing misfolded states. Exactly how the misfolded proteins trigger oligodendrocyte apoptosis and why they are harmful to the cell is currently uncertain. The other path involves a species that is misfolded and has to rearrange in an even slower step before the properly folded structure is reached. Interactions involving the exposed hydrophobic surfaces of misfolded protein conformers lead to the formation of toxic aggregates, including oligomers, protofibrils and amyloid fibrils. The red asterisk represents a site of modification on the misfolded protein as a result of one of these stresses. In some cases, chaperones promote the correct folding of their misfolded protein substrates. Complex formation with the chaperone thus allows the correction of misfolded conformations in an isolated environment without the danger of intermolecular aggregation reactions. Strikingly, the transgenic rats showed that misfolded protein tau triggered massive inflammatory response characterized by activation of microglia and macrophages. Moreover, paths that lead to misfolded, kinetically trapped species can also be seen.
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