methylate
In biological systems, methylation is accomplished by enzymes.
Maintenance of methylation patterns is necessary for normal development of mice.
No methylation was detected in benign tissue from breast cancer patients.
The methylation status of the gene did not correlate with the levels of protein.

SMART Vocabulary: related words and phrases

Chemistry - general words
acceptor
aerosol
aerosolize
allotrope
amphiprotic
balanced equation
chemical equation
electrolyte
endocrine disruptor
endothermic
epitaxial
epitaxially
epitaxy
inorganic chemistry
ionic bond
nonelectrolyte
nonreactive
preatomic
reactive
reactivity

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Genetics

Examples of methylation

methylation
However, antisense transcripts were still present after deletion and found to originate from other regions of maternal methylation.
Our observations suggest an association between separation of parental chromosomes and differential activities of methylation and demethylation during early embryonic development of the mouse.
However, the exact mechanism and function of methylation changes in such processes are substantially unknown.
The methylation sites that survive are part of the imprinting process, passing maternal and paternal information to the final germ cell populations.
Hypo-methylation results in the permanent overexpression of genes and is a feature of both aging25 and malignant cells.
Importantly, increased methylation was also detectable in numerous premalignant lesions.
A methylation assay with high specificity and sensitivity was developed, and a panel of breast tissue samples (n 175) was characterized for methylation status.
In eutherians, differential methylation of cis-regulatory regions is predominant.
Paramutation of the r1 locus of maize is associated with increased cytosine methylation.
Imprinted methylation and its effect on expression of the mouse zfp127 gene.
Here we used two drugs known to be involved (besides their side effects) in disturbance of the normal process of methylation status maintenance.
Such alterations are mediated by methylation processes that are triggered by environmental events.
Methylation has indeed been shown to accompany gene silencing in most of the mammalian, plant and filamentous fungal examples.
In addition to genetic changes, epigenetic alterations including methylation or imprinting could also lead to the somatic inactivation of candidate tumour suppressor genes.
In mature oligodendrocytes, the expression of inhibitory molecules is silenced by additional epigenetic modifications, including histone methylation and chromatin compaction.
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