| 词汇 | ligand |
| 释义 | ligand noun[ C ] specializeduk /ˈlɪɡ.ənd/ us /ˈlɪɡ.ənd/ chemistry an ion(= an atom or small group of atoms that has an electrical charge) or a molecule(= the simplest unit of a chemical substance) that is attached to a metal atom配位体 biology a molecule(= the simplest unit of a chemical substance) that is attached to another molecule配体 Physics: atoms, molecules & sub-atomic particles acceptor alpha particle anti-radical antilepton antimatter antineutrino beta decay beta particle hadron Higgs boson interatomic interelectronic interionic monatomic multi-molecular multiparticle muon neutrino positron relative atomic mass You can also find related words, phrases, and synonyms in the topics: Animal & plant biology - general words Examples of ligandligand The development of both types of ligands could therefore have important biomedical implications. Studies such as presented here can serve to provide the data necessary for application of opioid ligands in such unique settings. The sharing of these receptors by multiple cytokines raises the question of how the ligands can trigger specific responses in the target cells. Thus, the net effect of the mixture of the two ligands at the level of the whole animal will be the combined effect. The latter may either cooperate in binding heme or might bind distinct ligands. Our data in conjunction with those of other laboratories indicates the differences in orientation of different ligands within the same binding cleft. Polycystin-1 comprises multiple extra- and intracellular protein domains that suggest many different protein ligands and hence many different cellular functions. However, under nutrient limiting conditions in the environment, microorganisms may secrete ligands, such as siderophores, to scavenge trace metal micronutrients. However, the same trends in metal concentration and behaviour were observed in both biotic and abiotic components, indicating metal-specific ligands were not produced. In another possible application, these groups could be part of designed ligands, which may site-specifically penetrate the hydrophobic cores of proteins, possibly inactivating them. The option of facilitated transport of hydrophilic ligands to engage intracellular receptors is little used for signaling, however, suggesting that transmembrane receptors are more effective. What has largely failed is designing ligands based on known protein structure. Although there has been enormous progress toward accomplishing parts of the vision, the core problem - the design of ligands to bind proteins - has remained intractable. Overall, the interactions are characterised by enthalpy-entropy compensation mechanisms, as typically found for other groove-binding ligands. Acetylcholinesterase : role of the enzyme's charge distribution in steering charged ligands toward the active site. See all examples of ligand These examples are from corpora and from sources on the web. Any opinions in the examples do not represent the opinion of the Cambridge Dictionary editors or of Cambridge University Press or its licensors. |
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