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词汇 kinetochore
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Examples of kinetochore


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Protein dynamics at the kinetochore: cell cycle regulation of the metaphase to anaphase transition.
Suppose that a high threshold concentration of nocodazole is required to induce metaphase arrest, while only a much lower nocodazole concentration is needed to damage the spindle or kinetochore.
Human survivin is a kinetochore-associated passenger protein.
Clathrin aids in the congression of chromosomes by stabilizing kinetochore fibers of the mitotic spindle.
From
Wikipedia

This example is from Wikipedia and may be reused under a CC BY-SA license.
The spindle, to which the chromosomes are attached by kinetochores, is composed of microtubules, which are highly sensitive to temperature changes.
In conclusion, somatic cell nuclei are unable to go through meiotic division when introduced into oocyte meiotic cytoplasm, partly due to the abnormal kinetochore distribution.
Tension-sensitive kinetochore phosphorylation and the chromosome distribution checkpoint in praying mantid spermatocytes.
The checkpoint delaying anaphase in response to chromosome monoorientation is mediated by an inhibitory signal produced by unattached kinetochores.
In vitro matured oocytes arrested at second meiotic metaphase and kinetochores were detectable as paired structures aligned at the spindle equator.
The residual concentration of nocodazole would, however, still be high enough to damage the spindle or kinetochore.
Microinjected kinetochore antibodies interfere with chromosome movement in meiotic and mitotic mouse oocytes.
This may be due to the orientation of the kinetochores.
Abnormal kinetochore structure activates the spindle assembly checkpoint in budding yeast.
Taxol induces the assembly of free microtubules in living cells and blocks the organizing capacity of the centrosomes and kinetochores.
The spindle clearly possessed two poles with kinetochores present at each, indicating that the first zygotic nuclear division occurs in the developing zygote prior to ookinete formation.
Simerley et al. (1990) reported that microinjection of kinetochore antibodies interfered with chromosome movement and segregation of chromatin in either meiotic and mitotic mouse oocytes.
Kinetochore reproduction theory may explain rapid chromosome evolution.
Kinetochore chemistry is sensitive to tension and may link mitotic forces to a cell cycle checkpoint.


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