Examples of kinase

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Choline kinase down-regulation increases the effect of 5-fluorouracil in breast cancer cells.
These receptors are d e v o i d of any intrinsic kinase activity.
Unfortunately, the activity of these kinases was not significantly different from those measured in control oocytes (not shown).
Inhibition of protein kinases by 6-dimethylaminopurine accelerates the transition to interphase in activated mouse oocytes.
Several protein kinases have been shown to play a role in meiotic resumption.
Determination of kinase activity demonstrated decreasing enzyme activities.
The weaker kinase activity of procainetreated samples described earlier was confirmed by autoradiography.
The reasons for the dominance of kinase (and other enzyme) inhibitors as targets for modern cancer therapeutics are centred on the enzyme substrate-binding site.
Therefore, the inhibition of tau kinases may be a reasonable therapeutic strategy in the treatment of tauopathies.
Mitogen-activated protein kinase translocates into the germinal vesicle and induces germinal vesicle breakdown in porcine oocytes.
This has been expected since the histidine kinase family does not qualify on the sequence level as member of this superfamily.
The serum creatine kinase is grossly elevated, myoglobinuria may be evident, and there is a risk of acute renal failure.
Contribution of high p34cdc2 kinase activity to premature chromosome condensation of injected somatic cell nuclei in rat oocytes.
For example, many forms of cancer are caused by mutations of specific protein kinases.

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