| 词汇 | ischaemia |
| 释义 | ischaemia noun[ U ] medical specializedUK(USischemia)uk /ɪˈskiː.mi.ə/ us /ɪˈskiː.mi.ə/ a medical problem in which there is not enough blood flowing to a part of the body, usually because the arteries have become too narrow. It can lead to very serious health conditions: 局部缺血 cerebral/myocardial ischaemia大脑／心肌局部缺血 Disorders & diseases of the heart & blood acidosis acquired agammaglobulinemia adult-onset diabetes afib agammaglobulinemia anaemic apoplexy clot-busting coarctation of the aorta congenital erythropoietic porphyria congestive heart failure coronary heart disease decompression sickness furred MGUS mini-stroke mitral monoclonal gammopathy of unknown significance monocyte disorder toxaemia Examples of ischaemiaischaemia In preeclampsia, an inadequate placental trophoblast invasion of the maternal uterine spiral arteries results in poor placental perfusion, leading to placental ischaemia. During ischaemia, when oxygen supply is limited, the electron transport chain of the inner mitochondrial membrane becomes highly reduced. When tissues undergo ischaemia followed by the re-establishment of blood flow, leukocytes are key players in causing the resultant tissue injury. Both effects could theoretically contribute to ischaemia-reperfusion type injury of the placenta, but assessing their importance in vivo is complex. There was no clinical evidence of myocardial ischaemia in either case. As yet, there is no treatment for macular ischaemia. The amount of retinal ischaemia that is present will limit the potential treatment benefit. This process, in addition to sustained or episodic hypotension may induce cerebral hypoperfusion, ischaemia and hypoxia. Coronary artery disease can give rise to reversible diastolic dysfunction during periods of acute ischaemia in elderly patients. Increased intracellular calcium is an important early factor in the cell damage seen in cerebral ischaemia. The combination of asphyxia and ischaemia due to hypotension and hypoperfusion results in a decrease of cerebral oxygen consumption and, if sustained, brain damage. Pathophysiology of hypertension during preeclampsia linking placental ischaemia with endothelial dysfunction. The potential antioxidant and neuroprotective properties are offset by the theoretical risk of cerebrovascular ischaemia. Critical limb ischaemia with peripheral neuropathy is a frequent complication in diabetes. Nevertheless, in an attempt to produce pre-eclampsia in animals, investigators have experimentally induced uteroplacental ischaemia in a variety of species. See all examples of ischaemia These examples are from corpora and from sources on the web. Any opinions in the examples do not represent the opinion of the Cambridge Dictionary editors or of Cambridge University Press or its licensors. |
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