Examples of inactivation

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It is a most valuable tool in the biochemical laboratory due to the minimal denaturation or inactivation of biologically active compounds.
There is evidence for ecdysteroid production in the integument and pathways of hormone inactivation are similar to those in insects.
Understanding of the hormone biosynthetic and inactivation pathways (including their regulation) that are responsible for production of these mandatory changes in ecdysteroid profile is poor.
The cumulative inactivation of tumour suppressor genes and/or the amplification of oncogenes lead to progressively more malignant astrocytic tumours.
The amino terminus of a calcium channel b subunit sets rates of channel inactivation independently of the subunit's effect on activation.
The physical interaction between the soluble inactivation peptide* and the channel involves both electrostatic and hydrophobic contributions.
The reversal of this inactivation process is seen as recovery.
Contemplating total artificial heart inactivation in cases of futility.
However, prolonged treatments may result in the inactivation of viruses.
The major inactivation of biogenic amines is performed by monoamine oxidase, an enzyme located solely in mitochondria.
X-autosome translocations in the mouse : their characterisation and use as tools to investigate gene inactivation and gene action.
This inactivation step significantly reduced the release of water-soluble and oxalate-soluble pectins (data not shown).
Values were derived from 32 cells during control and 32 cells during pretectal inactivation.
However, in contrast to the activation, the inactivation was much slower (9-70 ms) and was voltage dependent.
If calcium influx is involved, then the inactivation should become more pronounced at negative potentials due to the increased driving force for calcium influx.
However, the effect was voltage-independent and likely mediated by modulation of the inactivation cascade of phototransduction.
As other currents gradually developed, the inactivation constant of this current is not cer tain.
The basis for this sustained current in tiger salamander retinal ganglion cells is unknown; perhaps it reflects a biphasic inactivation behavior of one channel type.

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