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词汇 galectin
释义 BETA

Examples of galectin


galectin isn’t in the Cambridge Dictionary yet. You can help!
Thus, galectin-1 may trigger different endpoints along the apoptotic pathways in different target cells.
This is consistent with the anti-apoptotic functions of galectin-3.
Some of these have been discovered or confirmed by using genetically engineered mice deficient in a particular galectin.
The mechanism by which galectin-3 regulates wound healing remains to be elucidated.
Thus, galectin-9 has the potential to be used as a therapeutic agent for treatment of rheumatoid arthritis, as well as other inflammatory diseases.
How interactions of galectin-1 with these glycans control its secretion remains to be elucidated.
Recombinant galectin-7 may likewise be used for this purpose.
The mechanisms by which endogenous galectin-3 regulates these activities still remain to be elucidated.
The structure revealed a fold with overall similarities to that of galectin-1 and -2, and to a greater extent that of galectin-10.
This suggests that simultaneous intra- and extracellular actions of galectin-3 may be required for wound healing.
In addition, the effect of galectin-9 on dendritic cell maturation is only slightly inhibited by lactose.
This effect was neutralised by soluble galectin-1 and its inhibitor, lactose.
The existing data suggest that recombinant galectin-1 could potentially be exploited as an effective therapeutic reagent for treating inflammatory and autoimmune diseases.
However, the functional consequences of these interactions have not been demonstrated definitely and directly from the galectin side.
As mentioned above, galectin-3 can form pentamers upon binding to multivalent glycans.
These studies provide evidence that galectin-1 promotes muscle differentiation.
The situation for galectin-3 is more complicated.
Given its known biological roles in tumour progression, galectin-1 has been postulated as an attractive target for anticancer therapies.
In galectin-4-depleted cells, protein markers of the apical membrane domain were trapped intracellularly, suggesting a defect in apical membrane protein sorting.


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