词汇 | acetylation |
释义 | BETA Examples of acetylationacetylation isn’t in the Cambridge Dictionary yet. You can help! In addition, functional properties of nuclear receptors, including tumor growth in vivo, are regulated by acetylation. In the first project, gene-expression profiles were analysed, whereas the second study was focused on histone acetylation status. The processes of acetylation and methylation rendered these derived aromatics lipophilic, and they were subsequently integrated into essential oils. Another important aspect in the process of gene expression related to learning and memory is acetylation. In this study we have directly assessed whether histone acetylation may be implicated in gene regulation at this domain. Here we investigate the role of histone acetylation, already shown to play an important role in dictating both local and widespread chromatin configuration. Post-translational modification by acetylation and phosphorylation are integrated in several physiological circumstances. The histones themselves, particularly their post-translational modification such as acetylation and phosphorylation, may also play a role. Acetylation of nuclear receptors occurs through a conserved motif. Acetylation of histones opens up the chromatin structure - a process essential for gene expression. Characterize the functional consequence of this interaction on global histone acetylation and on the expression levels of transcription factors. We detected allele-specific patterns of histone acetylation confined to the domain of differential nuclease sensitivity. Thus, these studies identify histone acetylation of neuronal gene promoters as a crucial event for differentiation. In no case did the acetylation level correlate with actual or potential transcriptional activity. Very limited data are available on the role of histone acetylation in ageing mammalian oocytes. Transitions in histone acetylation reveal boundaries of three separately regulated neighboring loci. As mentioned previously, p53 also interacts with enzymes that control histone acetylation, indicating a role for two main senescence mediators in the modulation of histone acetylation. |
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