Examples of filopodia

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The video shows the switch of a round cell, which bears blebs and filopodia, to a spread cell with ruffling activity.
The motility of elongated cells is driven by protrusive lamellipodia and filopodia on neurite-like, leading extensions.
Analysis of mesodermal cell morphology in those embryos showed a severe decrease in the number and complexity of cellular extensions such as filopodia and lamellipodia.
This change is typified by the extension of long, dendritic-like processes bearing protrusive regions of ruffling activity and filopodia, and by the downregulation of stressfibre bundles.
At the leading edge, filopodia and spikes protrude, relay cues in the adjacent environment into the cell body, and form transient adhesions that become enlarged and stabilised as lamellipodia.
The filopodia of pioneer glia were observed to extend in multiple directions, which indicates that these processes sense the environment to determine migratory direction.
During migration, the cells extend filopodia, and there is extensive ruffling at the leading edge.
Note the development of long extensions with tips bearing ruffles and filopodia (arrowheads).
Occasionally groups of four or five cells were noticed with some of the cells exhibiting filopodia and some blebs.
Axons of these cells have filopodia that appear to originate at one or two specific sites along the axon shaft.
Prominent stress-fiber bundles cross the cell body, and lamellipodia and filopodia protrusion actively at the cell edge.
Large lamellae extended around the cells and numerous filopodia were associated with these extensions of cell membrane.
The functional roles of filopodia have been m o s t widely studied in neuronal cells.
Highly-localized stimulation elicited the sprouting of filopodia, thread-like protrusions which likely later convert to dendritic spines.
Shape changes included extension of filopodia, ruffling of the edges, overall flattening of the cells, and obvious rapid movement.

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