| 词汇 | example_english_uric-acid |
| 释义 | Examples of uric acidThese examples are from corpora and from sources on the web. Any opinions in the examples do not represent the opinion of the Cambridge Dictionary editors or of Cambridge University Press or its licensors. Under normal conditions this membrane bound enzyme exists in the xanthine deydrogenase form, converting hypoxanthine to xanthine, and xanthine to uricacid. Unravelling the 'uricacid paradox' will be an interesting task. We humans have uricacid levels much higher than those of other primates, probably because it protects against oxidative tissue damage. Change of the rat xanthine oxidase/dehydrogenase and uricacid formation by aging and dietary restriction in the liver. The concentration of uricacid was found to be significantly higher in the human hydatid fluids compared with other cyst fluids. Cerebrovascular fluid levels of uricacid in dogs and the effect of allopurinol. Determination of uricacid and hematin in a single sample of excreta from blood-fed insects. Traces of uricacid and guanosine also were found in the faeces of some of the argasid ticks, but these compounds did not induce an arrestment response in the bioassays. Towards the physiological function of uricacid. Other well-documented effects included raised levels of potassium, blood sugar and uricacid. From the Hansard archive Example from the Hansard archive. Contains Parliamentary information licensed under the Open Parliament Licence v3.0 Very high levels of uricacid may affect the function of your kidney. From the Hansard archive Example from the Hansard archive. Contains Parliamentary information licensed under the Open Parliament Licence v3.0 However, prolonged hyperuricemia can cause uricacid nephropathy. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. It is a synthetic urate oxidase enzyme and acts by degrading uricacid. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. This can occur for a number of reasons, including diet, genetic predisposition, or underexcretion of urate, the salts of uricacid. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. It is considered as uricacid solid crystals and it is less toxic than urea. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Anchovy and its products like budu is high in protein and uricacid content, thus not recommended for people with gout condition. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Allowing the shark to fully decay and cure removes retained uricacid from the flesh, making it edible. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. In most living species, uricacid is excreted along with feces as a semisolid waste. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Inosine can be used to elevate uricacid levels. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Uricacid is a product of the metabolic breakdown of purine nucleotides. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. This painful condition is the result of needle-like crystals of uricacid precipitating in joints, capillaries, skin, and other tissues. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Uricacid is a protein metaporposis product of terrestrial invertebrates, birds and diapsids. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Some breakdown of the purine ring may also occur, forming uricacid. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Gout is essentially a disorder caused by precipitation of uricacid crystals in the joint. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. The bladder is small as nitrogenous waste is excreted as uricacid. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. It is the product of the oxidation of uricacid by urate oxidase. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. The name is for its composition, anhydrous uricacid. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. A chick on up to its 5th day of development excretes ammonia, from 5th to 9th day, urea and 9th day onwards, uricacid. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Thus, like a high purine diet, starvation increases the amount of purine converted to uricacid. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. The effect of fructose in reducing excretion of uricacid is increased in people with a hereditary (genetic) predisposition toward hyperuricemia and/or gout. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Causes of decreased excretion include kidney disease, certain drugs, and competition for excretion between uricacid and other molecules. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Apart from normal variation (with a genetic component), tumor lysis syndrome produces extreme levels of uricacid, mainly leading to renal failure. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. These waste products consist mainly of uricacid, urea and amino acids, and are normally converted into dry pellets before being disposed. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. It is caused by elevated levels of uricacid in the blood that crystallizes and deposits in joints, tendons, and surrounding tissues. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Boneset, although poisonous to humans and grazing livestock, has been used in folk medicine, for instance to excrete excess uricacid which causes gout. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. States of high cell turnover and alcohol ingestion are some of the most prominent cases of high serum uricacid concentrations. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Bilirubin comes from the breakdown of red blood cells' contents, while uricacid is a breakdown product of purines. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. People who suffer from gout or high uricacid in the blood should avoid eating such foods. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Two common conditions related to excess uricacid, gout and uricacid nephrolithiasis, are not features of tumor lysis syndrome. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Lowering uricacid levels can cure the disease. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Repeated attacks can be prevented by different drugs used to reduce the serum uricacid levels. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Thus, the diagnostic utility of measuring uricacid level is limited. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. It is caused by elevated levels of uricacid in the blood. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. The potential role of the pro-oxidant role of uricacid in (e.g.) atherosclerosis and ischemic stroke is considered above. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Filtration of the blood, reabsorption of ions and water, and secretion of uricacid are all components of the kidney's process. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. It can be used in patients of gout with hypertension as an antihypertensive because it decreases reabsorption of uricacid, while other diuretics increase it. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Several studies conclude that high uricacid levels, apart from other contributing factors, by itself may be a significant cause of insulin resistance. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. High blood concentrations of uricacid can lead to gout. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Sevelamer, a drug indicated for prevention of hyperphosphataemia in patients with chronic renal failure, can significantly reduce serum uricacid. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. On the other hand, plasma uricacid levels correlate with longevity in primates and other mammals. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. There are other vacuoles that may contain membranous inclusions, while still others contain crystalline material variously interpreted as oxalate crystals or crystalline uricacid. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. In birds, reptiles, and terrestrial snails, metabolic ammonium is converted into uricacid, which is solid and can therefore be excreted with minimal water loss. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Xanthine oxidase is responsible for the successive oxidation of hypoxanthine and xanthine, resulting in the production of uricacid, the product of human purine metabolism. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Birds excrete their nitrogenous wastes as uricacid in the form of a paste. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. The nephrocytes collect waste material such as uricacid and accumulate it in "renal vesicles" close to the digestive tract. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. These enzymes catalyze the oxidation of hypoxanthine to xanthine and can further catalyze the oxidation of xanthine to uricacid. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Allopurinol is a drug that inhibits the enzyme xanthine oxidoreductase and, thus, lowers the level of uricacid in the body. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. He studied the formation of urea and uricacid and the role of the liver in this process. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. It is essential that the overproduction of uricacid be controlled in order to reduce the risk of nephropathy, nephrolithiasis, and gouty arthritis. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Similarly, uricacid does not penetrate the bloodbrain barrier well. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. High levels of purines are known to increase uricacid production and may aggravate or lead to conditions such as gout. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Uricosurics are often used in the treatment of gout, a disease in which uricacid crystals form deposits in the joints. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. In women, use of combined oral contraceptive pills is significantly associated with lower serum uricacid. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Causes of hyperuricemia can be classified into three functional types: increased production of uricacid, decreased excretion of uricacid, and mixed type. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. A single molecule of uricacid can also remove four atoms of nitrogen, making it more efficient than ammonotelism and ureotelism. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Allantoin is five to ten times more water-soluble than uricacid making it easier for the kidneys to excrete. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. This is based on the theory that uricacid is a powerful reducing agent and likely an important human antioxidant, in high concentration in blood. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Excessive concentration of uricacid in the blood stream leads to gout. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. The triggers for precipitation of uricacid are not well understood. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. An evolutionary loss of uricase, which breaks down uricacid, in humans and higher primates has made this condition common. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. The antioxidant effects of uricacid have led researchers to suggest this mutation was beneficial to early primates and humans. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. They found extensive visceral gout, lesions and uricacid deposits in the liver, kidney and spleen, as well as deposits of diclofenac residue in tissues. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. This reduces the risk of precipitates, since allantoin is five to ten times more soluble than uricacid. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Hypoxanthine is oxidized to xanthine and finally to uricacid. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. The colorless crystals can be difficult to distinguish from uricacid crystals which are also hexagonal. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. A deficiency of uricacid has been implicated in this process. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. The breed club makes no mention of the option to breed dogs without the high uricacid genes on its website. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. In most other mammals, the enzyme uricase further oxidizes uricacid to allantoin. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. On the other hand, like other strong reducing substances such as ascorbate, uricacid can also act as a prooxidant. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Anchovies also contain a high level of uricacid, a build-up of which can cause the inflammatory condition known as gout. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Guanine is deaminated to xanthine which in turn is oxidized to uricacid. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. It cools the blood vessels in the unfeathered tarsi and feet, and causes white uricacid to streak the legs. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. The overproduction of uricacid is present at birth, but may not be recognized by routine clinical laboratory testing methods. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. In humans and higher apes, the metabolic pathway for conversion of uricacid to allantoin is not present, so the former is excreted. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. As well, because xanthine oxidase is a metabolic pathway for uricacid formation, the xanthine oxidase inhibitor allopurinol is used in the treatment of gout. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. They excrete nitrogen as the complex nitrogenous waste compound uricacid, and related derivatives. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Increased production of uricacid is the result of interference, by a product of fructose metabolism, in purine metabolism. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Several single nucleotide polymorphisms of this gene are known to have a significant correlation with blood uricacid. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. This is believed to be due to temperature-dependent precipitation of uricacid crystals in tissues at below normal temperature. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Rasburicase catalyses the conversion of uricacid to allantoin, an inactive metabolite of purine metabolism. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Xanthine is subsequently converted to uricacid by the action of the xanthine oxidase enzyme. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. In addition, renal function, uricacid and electrolytes, as well as liver enzymes, are commonly checked. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Plasma chemistry remains relatively stable with age but lower values of protein content, uricacid, cholesterol, triglycerides, and phospholipids were seen in free living flamingos. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. These examples are from corpora and from sources on the web. Any opinions in the examples do not represent the opinion of the Cambridge Dictionary editors or of Cambridge University Press or its licensors. |
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