| 词汇 | example_english_spindle-checkpoint |
| 释义 | spindle checkpointcollocation in Englishmeanings of spindleand checkpointThese words are often used together. Click on the links below to explore the meanings. Or, see other collocations with spindle. spindle noun[C] uk /ˈspɪn.dəl/ us /ˈspɪn.dəl/ a part of a machine around which something turns, or a rod onto which thread is twisted when it is spun (= made ... See more at spindle checkpoint noun[C] uk /ˈtʃek.pɔɪnt/ us /ˈtʃek.pɔɪnt/ a place where people are stopped and asked questions and vehicles are examined, especially at a border between ... See more at checkpoint Examples of spindle checkpointThese examples are from corpora and from sources on the web. Any opinions in the examples do not represent the opinion of the Cambridge Dictionary editors or of Cambridge University Press or its licensors. Meiotic spindle and spindlecheckpoint proteins are responsible for normal chromosome alignment and separation during meiosis. It is involved in microtubule attachment to chromosome centromeres and in the activation of the spindlecheckpoint during mitosis. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. During this process, kinetochores that are attached to the mitotic spindle but that are not under tension trigger the spindlecheckpoint. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Once activated, the spindlecheckpoint blocks anaphase entry by inhibiting the anaphase-promoting complex via regulation of the activity of mitotic checkpoint complex. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Shugoshin also acts as a spindlecheckpoint component. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Impaired spindlecheckpoint function has been found in many forms of cancer. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. This situation generates centromeric tension, and for this reason the spindlecheckpoint is not activated. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Upon microtubule-kinetochore attachment, a mechanism of stripping via a dynein-dynein motor complex transports spindlecheckpoint proteins away from the kinetochores. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Such a signal creates the mitotic spindlecheckpoint. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. During mitosis or meiosis, the spindlecheckpoint prevents anaphase onset until all chromosomes are properly attached to the spindle. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. The spindlecheckpoint system is a regulatory system that restrains progression through the metaphase-to-anaphase transition. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. An unattached kinetochore, and thus a non-aligned chromosome, even when most of the other chromosomes have lined up, will trigger the spindlecheckpoint signal. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Key tumor suppressors such as p53 also play a role in the spindlecheckpoint. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Both the monotelic and the syntelic configurations fail to generate centromeric tension and are detected by the spindlecheckpoint. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. These examples are from corpora and from sources on the web. Any opinions in the examples do not represent the opinion of the Cambridge Dictionary editors or of Cambridge University Press or its licensors. Want to learn more? Go to the definition of spindle Go to the definition of checkpoint See other collocations with spindle |
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