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词汇 example_english_null-allele
释义

null allele

collocation in English

meanings of nulland allele


These words are often used together. Click on the links below to explore the meanings. Or, see other collocations with allele.
null
adjective
uk /nʌl/ us /nʌl/
having no ...
See more at null
allele
noun[C]
uk /əˈliːl/ us /əˈliːl/
a gene that is found in one of two or more different forms in the same position in a chromosome, and so produces a particular characteristic that can be different for different people, such as ...
See more at allele


Examples of null allele


These examples are from corpora and from sources on the web. Any opinions in the examples do not represent the opinion of the Cambridge Dictionary editors or of Cambridge University Press or its licensors.
In this case the data were analysed as a three-allele system (two scoreable alleles and a non-scoreable nullallele).
However, in many applications, a nullallele is not the most physiologically relevant mutant form of the gene.
Some of these apparent homozygotes could be heterozygotes with a nullallele.
First, the occurrence of a nullallele at an enzymatic locus will lead heterozygotes between a functional and the nullallele to be scored as homozygotes.
This may be useful when working with a specific set of data for which the choice of markers is limited, with evidence of a single nullallele.
Another possible explanation is that there is one nullallele at each of the loci used and this is not accounted for in the pseudo-likelihood calculation.
One allele is a non-functional nullallele, while the other encodes for a partially active enzyme.
From
Wikipedia

This example is from Wikipedia and may be reused under a CC BY-SA license.
At the phenotypic level, a nullallele is indistinguishable from a deletion of the entire locus.
From
Wikipedia

This example is from Wikipedia and may be reused under a CC BY-SA license.
If a mutation occurs in the annealing site, then the marker can no longer be used and the allele is turned into a nullallele.
From
Wikipedia

This example is from Wikipedia and may be reused under a CC BY-SA license.
For allozymes, null alleles can be generated by mutations or deletions within a gene and thus do not produce any detectable protein.
However, the presence of null alleles is less likely here, because null phenotypes were not detected.
The obvious cause of an apparent excess of homozygotes is the presence of one or more null alleles.
These examples are from corpora and from sources on the web. Any opinions in the examples do not represent the opinion of the Cambridge Dictionary editors or of Cambridge University Press or its licensors.
Want to learn more?
Go to the definition of null
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See other collocations with allele
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