Examples of malignant

Example from the Hansard archive. Contains Parliamentary information licensed under the Open Parliament Licence v3.0
Other more traditional topics such as neuroleptic malignant syndrome and extrapyramidal syndromes are also expertly covered with enough neuropharmacology to make the relevant pathophysiology comprehensible.
Malignant gliomas are characterized by rapid cell proliferation, a high level of invasiveness into the surrounding brain and increased vascularity.
Metastases were not found in the patient with the malignant angiosarcoma.
Metastasis results from preexisting variant cells within a malignant tumour.
Malignant melanoma can arise de novo and may present as an irregularly pigmented lesion with an irregular edge.
An ulcer which fails to heal despite adequate therapy should be biopsied to exclude malignant change.
Malignant melanoma and skin lymphoma are also important tumours in the elderly.
Influence of the number of malignant regional lymph nodes detected by endoscopic ultrasonography on survival stratification in esophageal adenocarcinoma.
Accelerated radiotherapy regimen for malignant gliomas using stereotactic concomitant boosts for dose escalation.
The advantage of beta 2 microglobulin estimation is offset by its non-specific rise in certain inflammatory and malignant conditions.
The chance of malignant degeneration in a benign papillioma is not well understood.
A disagreement between two competent practitioners is malignant if and only if it is not benign.
Malignant change such as the development of squamous cell carcinoma is common.
The responses of normal and malignant tissues to changes in fraction size are non-linear and are well described using a linear quadratic model [10].
Quantification of membrane and membrane-bound proteins in normal and malignant breast cancer cells isolated from the same patient with primary breast carcinoma.
The risk of subsequent malignant degeneration of a papilloma is another consideration.
The authors concluded that a defective modulation ofventricular repolarization may favor the onset of malignant arrhythmias and result in sudden death.
The lesion was interpreted as a malignant spindle cell tumor and a metaplastic carcinoma was favored, however, the possibility of sarcoma could not be excluded.
Randomized trial of three chemotherapy regimens and two radiotherapy regimens in postoperative treatment of malignant glioma.
High-dose chemotherapy and autologous bone marrow rescue followed by interstitial and external-beam radiotherapy in newly diagnosed pediatric malignant gliomas.
Initial findings were obtained in leukemias: and subsequently in solid tumors, including malignant gliomas.
Most are systemically well although there is an association with malignant disease and immunosuppression.
How often neuroleptic malignant syndrome really does occur in elderly people with dementing illnesses treated with neuroleptics is not clear.
A recent retrospective review compared the outcomes of open or laparoscopic gastrojejunostomy versus endoscopic stenting for malignant gastric outlet obstruction.
Unfortunately, she developed a highly malignant bladder cancer.
Second, the majority of studies have tended to focus on patients with malignant disease, so little is known about depression in other life-limiting illnesses.
How was life after treatment of a malignant brain tumor?
The remaining studies correlating p53 and time to event, and p53 and response, in malignant epithelial ovarian cancer were systematically evaluated.
A definite diagnosis was assigned when there was a proven cause and effect (such as malignant cells found in the pericardial fluid).
In the patient the enzyme efficiently converts the prodrug ganciclovir to a substance that is toxic only to replicating malignant cells.
Two of the protocols directly target malignant cells, and one protocol targets immune cells.
Patients with malignant, severe, or psychiatric diseases who were unable to communicate or who refused to participate were excluded.
Curative treatment focused mainly on patients with aggressive malignant lymphomas, acute myelogenous leukemia, and cancer in the breast and ovaries.
From 1987 to 1994, 1.1 million women were referred for screening; malignant tumors were found in 3,503 women (0.36%) (9).
Malignant tumors are found only exceptionally in children, with primitive sarcomas being the most frequent.
As malignant lesions can masquerade as benign and vice versa, there can be overlap in the imaging characteristics of benign and malignant lesions.
Current therapy for malignant disease is mostly based on surgery, chemotherapy and radiotherapy, and there is an urgent need for new therapeutic approaches.
In this study, we examine how a specialist nurse assists patients with malignant glioma and their families.
Psychosocial variables associated with the exceptional survival of patients with advanced malignant disease.
Two cancer patients who developed neuroleptic malignant syndrome, a potentially lethal adverse reaction of psychotropic drugs, have been reported previously.
Similarly, 69.1% reported a reluctance to prescribe strong opioids for chronic non-malignant pain, which was a significantly greater reluctance than for cancer pain, for example.
They were also asked how 'reluctant' they were to prescribe opioid analgesics for chronic non-malignant pain, cancer pain and acute pain, using the same scale.
The exact mechanisms by which malignant disseminated strongyloidiases are caused during various types of immunodeficiencies are not well understood.
However, one of the cancers of the remaining six hamsters was highly malignant with invasion occurring into the diaphragm (fig. 3).
In mummies, malignant neoplasms should be more easily detected and diagnosed than in skeletal material.
Here volunteers were subject to infection by a particularly dangerous strain of malignant tertian malaria.
The infancy and childhood risks of congenital lung masses being managed conservatively include infection, bleeding, pneumothorax and malignant transformation.
Based on their map position, several of them were localized to regions involved in deletions and\\or translocations associated with both developmental and malignant disorders.
They are regarded as being locally malignant and can be severely disfigured if left untreated [9,10].
High-dose multi-agent chemotherapy followed by bone marrow rescue for malignant astrocytomas of childhood and adolescence.
Two other patients died, one of malignant lymphoma after 5 years and the other of gastric cancer after 8 years.
Five days to one month later, all of the infants came down with malignant tertian malaria.
Hypo-methylation results in the permanent overexpression of genes and is a feature of both aging25 and malignant cells.
The main mortality sources are diseases of the cardiocirculatory system (40%), malignant tumors (25.1%), respiratory diseases (9%), gastroenterology diseases (5.6%), and trauma plus poisoning (5.1%).
Surgery of a mass that was radiologically diagnosed as malignant resulted in true-positive or false-positive results.
Early detection or secondary prevention of cancer is increasingly important for the control of certain malignant diseases.
There appears to be a common pathway toward death for malignant and nonmalignant diseases.
The inclusion criteria were incurable malignant disease, aged over 18 years, and a predicted survival time of 2-9 months.
We need to think about the medium as more than just a source of in-uence, neither simply benign nor malignant.
The cardiac abnormalities were unique (42%) or multiple (58%) and represent a substratum for a malignant ventricular dysrythmia which may explain the sudden death.
Recovery was uneventful for 48 hours, but probable drug induced malignant hyperthermia lead to ventricular tachycardia and death.
Malignant tumours feel harder that benign ones and this physical property is related to their coefficient of elasticity.
According to others, mitral stenosis, when present, is secondary to an early onset and a malignant course of the disease.
In particular all graphics inside the malignant frown or the spadesuit have finite cyclicity.
Such mutated stem cells that escape apoptosis or senescence become at risk of malignant transformation.
Second, t h e risk of malignant disease associated with persistent infection would be likely to remain.
Malignant tumours within this group (ovarian carcinomas) are responsible for most of the morbidity and mortality due to ovarian cancer.
Identification of a mutation in the porcine ryanodine receptor that is associated with malignant hypothermia.
Typically, malignant glioma is a brain tumor with a poor prognosis; few patients survive more than two years after diagnosis.
The role of religious and spiritual beliefs in coping with malignant melanoma.
Open biopsy rates and benign-to-malignant biopsy ratios are computed by 17 and 16 countries, respectively.
Most brain tumours are malignant, with 25% proving to have spread from another (advanced) cancer, the most common being bronchus and breast (14).
Asymptomatic hemorrhage occurred in two patients and one death resulted from malignant cerebral edema.
Twenty of these came from eyes enucleated for malignant melanoma.
In this study, we took no account of the appropriateness or actual effectiveness of opioid medication prescription for chronic non-malignant pain.
Inclusion of these in survival analyses is not appropriate f o r studying effects of chemotherapy on malignant epithelial ovarian cancer because they could obscure correlations.
The altered pattern of localisation in tumour cells may help to disrupt the intercellular adhesion of colonocytes, resulting in the disorganised growth and movement of malignant cells.
A direct or indirect effect of tetraspanins on integrin function might lead to alterations of adhesion or migration properties of the malignant cells that could modify their metastatic potential.
The importance of immune senescence in the incidence and malignant properties of cancer in hosts of advanced age.
An analysis of doseeffect relationship in the radiotherapy of malignant gliomas.
A good writer, or speaker, knows a barbarism when he sees one, and realises that not all of them are malignant.
In recent years, a new generation of cancer therapies has emerged, based on a growing understanding of the molecular events that contribute to malignant transformation.
The patient population included solely malignant epithelial ovarian carcinoma.
The case was that of a 77-year-old woman with a 2 cm palpable mass, which appeared malignant on mammogram.
As with morphologic analysis, malignant lesions can exhibit benign kinetics and vice versa.
Heterogeneous enhancement is more characteristic of malignant lesions especially if rimenhancement is present.
The cumulative inactivation of tumour suppressor genes and/or the amplification of oncogenes lead to progressively more malignant astrocytic tumours.
They are located near the auditory canal and cerebellopontine angle, adjacent to the brainstem, making tumours 'malignant by position'.
Evidence of malignant neoplasm is extremely rare in antiquity, judging from the thousands of skeletons and mummies which have been examined.
Our duration of follow-up is short and malignant ventricular arrhythmias were not seen in either group on 24 hrs ambulatory electrocardiographic monitoring.
The final population included 35 women and 7 men, the majority of whom suffered from malignant breast tumors (34 persons).
Talking about death with children who have severe malignant disease.
A distinction was made between excision of a benign lesion (excision biopsy) and of a malignant lesion (curative, malignant surgery).
Malignant blood disorders with associated anaemia, such as myelodysplasia and leukaemia, become more frequent with advancing age.
Symptoms of malignant hypercalcaemia are often non-specific in older people.
These examples are from corpora and from sources on the web. Any opinions in the examples do not represent the opinion of the Cambridge Dictionary editors or of Cambridge University Press or its licensors.