| 词汇 | example_english_leptin-resistance |
| 释义 | leptin resistancecollocation in Englishmeanings of leptinand resistanceThese words are often used together. Click on the links below to explore the meanings. Or, see other collocations with resistance. leptin noun[U] uk /ˈlep.tɪn/ us /ˈlep.tɪn/ a hormone (= a chemical made in the body) that controls feelings of hunger and the way the body ... See more at leptin resistance noun uk /rɪˈzɪs.təns/ us /rɪˈzɪs.təns/ the act of fighting against something that is attacking you, or refusing to ... See more at resistance Examples of leptin resistanceThese examples are from corpora and from sources on the web. Any opinions in the examples do not represent the opinion of the Cambridge Dictionary editors or of Cambridge University Press or its licensors. Therefore, agerelated leptinresistance may be caused by increased adiposity or prolonged exposure to the elevated leptin, or both. There are several possible mechanisms for ageassociated leptinresistance, including alterations in leptin-accessibility to the central nervous system and hypothalamic response to leptin during aging. Another possibly effective approach that could overcome age-related leptinresistance is the activation of signalling pathways downstream of the hypothalamic leptin receptors. It is still unknown whether lifelong exercise can prevent the development of leptinresistance during aging. Some evidence suggests that prolonged exposure to the elevated level of leptin may play a causative role in agerelated leptinresistance. The role of leptinresistance in the lipid abnormalities of aging. Thus, approaches that could reverse or prevent leptinresistance would be attractive candidates. Collectively, aging is associated with leptinresistance, and reduced sensitivity to leptin occurs in middle age. When low birthweight offspring are permitted rapid catch-up growth by nutrient availability, these offspring will demonstrate evidence of increased body weight and body fat, and leptinresistance as adults. Impairments in leptin sensitivity (leptinresistance) become evident at relatively early age (by middle age) in parallel with age-associated elevation in leptin in rodents. Aging is clearly associated with leptinresistance that could play a causative role in age-associated neuroendocrine and metabolic impairments. The changes that occur in the hypothalamus to result in leptinresistance in obesity are currently the focus of obesity research. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Holtorf treats leptinresistance in patients with a class of medications that are typically reserved for controlling blood sugar levels in diabetics. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. These knock-out mice were hyperphagic which led to obesity, partial leptinresistance, increased adipose deposition, insulin resistance and impaired glucose tolerance. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Such leptinresistance may translate into diseases, notably it could be responsible for obesity in humans who have high levels of leptin. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Leptinresistance plays a role in the process where appetite overrules the message of satiety. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Leptinresistance can be triggered in rats by ad libitum consumption of energy-dense, highly palatable foods over a period of several days. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Yet another proposed mechanism involves the phenomenon known as leptinresistance. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. He demonstrated that human obesity is not characterized by leptin deficiency but by leptin resistance and helped usher in leptinomania in the study of obesity. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. These examples are from corpora and from sources on the web. Any opinions in the examples do not represent the opinion of the Cambridge Dictionary editors or of Cambridge University Press or its licensors. Want to learn more? Go to the definition of leptin Go to the definition of resistance See other collocations with resistance |
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