| 词汇 | example_english_histone-modification |
| 释义 | histone modificationcollocation in Englishmeanings of modificationThese words are often used together. Click on the links below to explore the meanings. Or, see other collocations with modification. modification noun uk /ˌmɒd.ɪ.fɪˈkeɪ.ʃən/ us /ˌmɑː.də.fəˈkeɪ.ʃən/ a change to something, usually to ... See more at modification Examples of histone modificationThese examples are from corpora and from sources on the web. Any opinions in the examples do not represent the opinion of the Cambridge Dictionary editors or of Cambridge University Press or its licensors. Pioneer factors can play a role in this by binding specific enhancers and flagging histonemodification enzymes to that specific gene. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. This histonemodification is used as a marker of promoters, using it to map these elements in the human genome. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Methylation, along with histonemodification, is central to imprinting. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Histonemodification is now considered a major regulatory mechanism that is involved in many different stages of genetic functions. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. In some cases, similar processes associated with histonemodification have been observed to transcriptionally upregulate genes. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. The choice of telomere maintenance mechanism may be influenced through epigenetic mechanisms and changes in histone modifications, possibly during tumourigenesis. To a large extent, differences in transcription factor binding are determined by the chromatin accessibility of their binding sites through histonemodification and/or pioneer factors. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. However, in perennial, iteroparous relatives the histonemodification rapidly disappears when temperatures rise, allowing expression of the floral inhibitor to increase and limiting flowering to a short interval. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. The pore-forming activity is not involved in causing the histone modifications. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. The collective set of histone modifications in a given cell is known as the histone code. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Studies on histone modifications may reveal many novel therapeutic targets. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Because the sub-field of histone modifications is relatively new, there aren't many results yet. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Recent provocative studies point to a key function of chromatin structure and histone modifications in alternative splicing regulation. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Differing histone modifications are likely to function in differing ways; acetylation at one position is likely to function differently from acetylation at another position. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Pioneer factors can also be associated with recruiting transcription-activating histone modifications. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Based on the "histone code" hypothesis, distinct covalent histone modifications can lead to functionally distinct chromatin structures that influence the fate of the cell. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Later, this idea was almost forgotten, until the experimental evidence has indicated a possible role of covalent histone modifications as an epigenetic code. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. A recent study of about 40 histone modifications across human gene promoters found over 4000 different combinations used, over 3000 occurring at only a single promoter. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. The second category is histone modifications. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. Deimination regulates gene expression through histone modifications. From Wikipedia This example is from Wikipedia and may be reused under a CC BY-SA license. These examples are from corpora and from sources on the web. Any opinions in the examples do not represent the opinion of the Cambridge Dictionary editors or of Cambridge University Press or its licensors. Want to learn more? Go to the definition of modification See other collocations with modification |
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